Utility Of 2-Amino-4,5,6,7-Tetrahydrobenzo[b]Thiophene-3- Carboxylic Acid In The Synthesis Of Novel Thieno[2,3-b] [1,2,4]Triazepinones And Thieno[2,3-d][1,3,4]Thiadiazolo [2,3-b]Pyrimidinones
نویسندگان
چکیده
A new series of thienothiadiazolopyrimidinone 4 was prepared via the reaction of hydrazonoyl chlorides 2 with 2amino-tetrahydrobenzo[b]thiophene-3-carboxylic acid 1 followed by cyclization with 1,1`-carbonyldiimidazole. Furthermore, benzothienothiadiazolo pyrimidinone derivatives 11a-c were prepared. The structure of the newly synthesized compounds were established on the basis of spectral data (Mass, IR, H and C NMR) and elemental analyses.
منابع مشابه
Synthesis and Antimicrobial Studies of Some Novel Bis-[1,3,4]thiadiazole and Bis-thiazole Pendant to Thieno[2,3-b]thiophene Moiety
The synthetic utility of 3,3'-(3,4-dimethylthieno[2,3-b]thiophene-2,5-diyl)bis (3-oxopropanenitrile) (1) in the synthesis of some novel bis-[1,3,4-thiadiazole] 6a-g and bis-thiazole 10 and 13 derivatives with thieno[2,3-b]thiophene moiety is reported. Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed promising results.
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